Anti-cancer treatment is rapidly entering the era of precision medicine

Gastric cancer is one of the common malignant tumors in China. Its incidence rate ranks second in China's malignant tumors, and its mortality ranks third. However, at present, the domestic market for gastric cancer chemicals is still very young. Let's analyze the 20 billion yuan drug market for gastric cancer and see who can win in the era of precision medicine .

Anti-cancer treatment is rapidly entering the era of precision medicine , causing market changes. According to the US version of the Precision Medical Program, the key to precision medicine in the field of anti-cancer therapy is gene sequencing , tumor, and personalization; and chemical drugs for treating stomach cancer are still extremely important categories.

In April 2014, the US FDA approved the Eli Lilly antibody drug Ramucirumab (Remoulezumab) injection, market name Gyramza. This is a humanized monoclonal antibody for specific blockade of vascular endothelial growth factor receptor 2 (VEGFR2) and downstream angiogenesis-related pathways for the treatment of advanced gastric cancer or gastroesophageal junction adenocarcinoma. However, in the past five years, the US FDA has not approved the marketing of small molecule new drugs for the treatment of gastric cancer.

Anti-cancer treatment is rapidly entering the era of precision medicine

Fortunately, Jiangsu Hengrui Medicine independently developed the national 1.1 new drug “Apatinib mesylate” and obtained the new drug certificate issued by the State Food and Drug Administration (CFDA) on November 3, 2014. Production registration. This is another major breakthrough in the field of anti-tumor in China, and it has also added new vitality to the targeted drug therapy market for advanced gastric cancer.

The stomach cancer market is not lonely

Gastric cancer is one of the common malignant tumors in China. The latest data released by the World Health Organization's International Agency for Research on Cancer shows that in 2012, there were about 446,500 new cases of gastric cancer in China, accounting for 47% of the world. Its incidence rate ranks second in China's malignant tumors, and its mortality ranks third.

With the development of a global aging society and the influence of human diet and ecological environment, it is expected that by 2025, the number of new cancer cases worldwide will rise to more than 19 million. The cancer situation in Asian countries should not be underestimated, and it will become the focus of growth. Among them, the incidence of gastric cancer in China's coastal cities and northwestern regions is relatively high.

With the application of new drugs and the advancement of combination therapy, the mortality rate of males and females in China has decreased significantly in recent years, with males dropping 21.4% per year and women dropping 21.1% annually. Despite this good trend, with the arrival of the aging population, China has a large population base. Experts predict that by 2030, China will have more than 5 million new cancer cases and 3.86 million annual deaths. The field of malignant tumor treatment is still a high-profile market.

The contest between the magic and the Tao

In recent years, after the release of the "Guidelines for the Standardization of Diagnosis and Treatment of Gastric Cancer" in China, the gastric cancer chemotherapy market has undergone certain changes. On the basis of traditional concurrent chemoradiotherapy with platinum, fluorouracil and its analogues, new adjuvant chemotherapy, postoperative adjuvant chemotherapy and palliative chemotherapy were proposed.

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