According to Caijing magazine, as of September 2016, a total of 32 precision medical companies have completed financing, including 20 in the A round, 11 in the B round, and 1 in the C round. A total of 9 companies have received more than 100 million yuan in financing. Most of these are gene sequencing companies, lacking core technologies and better business models. There is a fierce discussion in the industry recently about whether there is a “bubble†around gene sequencing.
Is the field of gene sequencing really overheated?
Sharing investment and investing investment investment manager Zhang Yaoyang has a deep understanding of the field of gene sequencing, he will answer a few key questions in the following sharing:
What is genetic sequencing? What are the main applications?
What companies in the industry can build their own competitive barriers?
Is the genetic sequencing industry overheated?
In recent years, although the National Health and Family Planning Commission and the CFDA have strengthened supervision over the clinical application market for genetic testing, there are currently more than 200 companies and institutions engaged in genetic testing related businesses in the domestic market. The following are some of the existing genetic testing services available online:
Huada Gene, Boao Bio, Berry and Kang, Nuohe Zhiyuan, Carbon Cloud Intelligence, Shihe Gene, Panshengzi, Jiyinjia, Baimaike Bio, Shenggu Tongchuang, Compson, Jiabao Renhe , Yiyi Gene, Boao Biological, Shengting Group, Sino-American Taihe, Skell Gene, Huaniu Bio, Micro-Spin Gene, Anuoyouda, Jiyun Wellcome, Aipuyi, Mackinaw Gene, Quantitative Health, Nosai Gene, Yi Xinxing, Boheng Bio, Baimai Huakang, Huasheng Hengye, Lusida, Xinnuomei, Zhongke Zixin, Heckville, Reidba, Yingmuhe, and traceability , Huayi Biology, Ovison, Bustan, CIGNA, Galaxy Gene, Warner Age, WuXi PharmaTech, Yunhe Health, Paisenuo Bio, Jingneng Bio, Meiji Bio, Proton Bio, Fandi Biology, 佰真生物, Southern Gene, Intense Ice Technology, Bio-Bio, Dingjing Bio, Sharp 翌 Gene, OU Yi Bio, Han Yu Bio, Pan Asia Gene, Uniman, Union Gene, Gima Bio, Kang Cheng Bio , Sai'an Bio, Jikai Gene, Shanghai Minxin, Aqu Bio, Boyuan Bio, Fengxun Information Biotech, Yingbai Bio, Lingke Bio, Quanmai Bio, Zhuoli Bio, Damai Bio, Gene Technology, Kelon Bio, Yuanqi Bio, Saiyou Bio, Xiangya Medical Laboratory, Hipiji Bio, Jikai Gene, Baishijia, Paihang Bio, Idea Di, Ruiqi Bio, Huiyan Bio, Jiayin Bio, Yunying Medical , Rainbow Trout, Jieyi Bio, Xiangyin Bio, Bohao Bio, Millennium Gene, Boda Wellcome, Yi Gene, Haipulus, Bohai Gene, Yuce Bio, Blueprint Gene, Puyuan Technology, Early Know Technology, Inmanu Bio, Hengchuang Gene, Rio Kangchen, Huayinkang, Daan Gene, Tuo Gene, Benchmark Medicine, Ruibo Bio, Burning Stone Technology, Kiddio Bio, Yongnuo Bio, Kuntu Bio, Meg Bio, Golden Field Test, Ruike Gene, Sai Zhe Bio, Hongxiang Bio, Beida Pharmaceutical , Guhe Bio, Zhejiang Tianke, Zhonghan Jinnuo, Hangzhou Yingrui, Hao Fund, Ran Sodium Bio, Jingjing Bio, Lianchuan Bio, Alto Bio, Aidekang Medicine, Dean Diagnostics, Bo Sheng Bio, Philippines Sand Gene, Kangsheng Global, Bena Gene Beauty of Life, Digital Bridge Technology, Jinao Bio, Volkswagen Source, Panomik Bio, Jin Weizhi Bio, Bethi Bio, Tianzhu Bio, Suzhou Biomedical Innovation Center, Qiagen, Saiye Bio, Zhongyi Jinda, Yikang Gene, Solomon Brothers Medicine, Di Kang Jinnuo, Guanghe Bio, Subo Bio, Rui Chuang Bio, Jianhai Biology, Pangu Gene, Tianjin Biochip, Guoxin Kyle, Pilot Drugs...
Gene sequencing, or DNA sequencing, refers to the analysis of the base sequence of a specific DNA fragment, that is, the determination of adenine (A), thymine (T), cytosine (C), and guanine (G) on DNA. Arrangement. Here, gene sequencing is mainly to distinguish between two concepts, gene detection and gene sequencing. These two concepts are easier to confuse.
Genetic testing includes: PCR, FISH, chip technology, gene sequencing. Gene sequencing technology is a type of genetic testing. Gene sequencing currently has one generation of sequencing (Sanger sequencing), second generation sequencing (illumina/Life Tech), and third generation sequencing (single molecule sequencing). PCR, FISH and chip technology, mainly through the known sequence to investigate the presence or absence of a specific sequence or site, focusing on the "detection", while the gene sequencing technology is to nucleotide the gene sequence one by one. Tested out, the focus is on "measurement." In comparison, gene sequencing is the most accurate, and as the cost of gene sequencing declines, the final sequencing technology will replace the first three technologies. The most widely used is the second generation sequencing, namely NGS.
In the whole gene sequencing industry, upstream instrument manufacturing has been monopolized by a few companies such as illumina and life tech. Most of the kit products in the middle and upper reaches do not have technical barriers, so the main opportunities are in the service applications of the middle and lower reaches.
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