It was learned from the National Health and Family Planning Commission that China responded to the WHO resolution and will implement a new polio (polio) vaccine immunization strategy on May 1 this year to stop the live attenuated trivalent polio vaccine with divalent ridges. Replacement of live attenuated gray vaccines and incorporation of polio inactivated vaccines (IPVs) into national immunization programmes.
According to the relevant person in charge of the National Health and Family Planning Committee, the poliovirus has three serotypes of type I, type II and type III. The corresponding vaccine also needs a vaccine strain containing three serotypes, namely a trivalent polio vaccine. Since 1965, China has inoculated a live attenuated oral polio vaccine (OPV) nationwide, and in 2000 it passed the WHO certification to achieve the goal of no polio, but due to the prevalence of poliovirus in neighboring countries, In order to prevent the occurrence of polio input cases, China has continued to use live attenuated trivalent polio vaccine since 2000. In 2015, the World Health Organization announced that type II poliovirus has been eliminated globally, and it is no longer necessary to inoculate a live attenuated vaccine containing type II strains. To this end, the World Health Organization decided to discontinue the live attenuated trivalent polio vaccine globally, switching to a live bivalent live attenuated vaccine containing both serotypes I and III, and requiring countries to introduce at least one dose of polio. Inactivate the vaccine. The adjustment, including 155 countries still using polio live attenuated vaccines, including China, was implemented simultaneously.
After the adjustment of the polio vaccine immunization strategy on May 1, China will implement the immunization program of “1 dose of IPV+3 doses of OPVâ€, that is, the children's four polio vaccinations, one dose of poliovirus inactivated vaccine, and the other three inoculations. Live attenuated vaccine.
According to experts, OPV is made from a vaccine strain screened after virulence reduction of the poliovirus strain by cell passage, and contains attenuated poliovirus. IPV is usually made by inactivation of a selected poliovirus strain or a polio vaccine strain. The combination of IPV and OPV provides better protection for children, which helps to reduce the incidence of related cases caused by live polio vaccine, and also reduces the risk of poliovirus input and transmission.
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