A recent study by researchers at the University of Tokyo, Japan, found that a substance in the brain called "cancer in the brain" can suppress the symptoms of epilepsy in experimental rats. This discovery is expected to help develop new anti-epileptic drugs.
"Intracerebral marijuana", also known as "endogenous cannabinoids", is a type of chemical substance originally found in the brain. It has a similar effect to cannabinoids in natural cannabis and regulates synaptic transmission signals. 2-AG is the most important type of "marijuana in the brain."
The University of Tokyo professor Kano Nobuo et al. used genetic techniques to develop experimental mice that could not synthesize 2-AG in the brain and compared them with normal experimental mice. When the rats were induced to have symptoms of epilepsy, the experimentally treated mice were more likely to develop the disease than the normal rats, and the symptoms of sputum were more serious.
The researchers said that epilepsy is a chronic brain disease, and the experimental results show that 2-AG "intracerebral marijuana" strongly inhibits epilepsy, and this result will help reveal epilepsy pathology and develop new therapeutic drugs. The research results have been published in the online edition of the new US Cell Report.
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