US research found that tears can be used to diagnose Parkinson's disease

Medical Network February 28, a new study in the United States found that by detecting the protein in tears, it is expected to diagnose people with Parkinson's disease.
Research papers will be included in the annual meeting of the American Academy of Neurology, which will be held in late April. The author of the paper, Mark Lu and his research team at the Keck School of Medicine in Southern California, USA, pointed out that there are many proteins produced by the lacrimal gland secreting cells in the tears. It is the nerves that promote the production of these proteins, and Parkinson's disease can affect the nerves. The function of the system.
The team compared the tears of 55 patients with Parkinson's disease with the tears of 27 healthy people and found differences in alpha-synuclein and oligoalpha-synuclein levels between the two groups. Among them, patients with Parkinson's disease have decreased alpha-synuclein levels, but elevated levels of oligoalpha-synuclein.
Lu said: "The process of Parkinson's disease may have occurred several years or decades before the onset of symptoms. The biological marker of tears helps to diagnose and even treat the disease early."
Parkinson's disease is a neurodegenerative disease common in middle-aged and elderly people, with an average age of onset of about 60 years. Alpha-synuclein is a soluble protein expressed presynaptic and perinuclear in the central nervous system and is associated with the pathogenesis and related dysfunction of Parkinson's disease.
Researchers believe that this study shows for the first time that tears can be a reliable, inexpensive, non-invasive biomarker for Parkinson's disease. However, they also need to test more people to determine if these proteins have changed in the earliest stages before the symptoms of Parkinson's disease.

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