According to Xinhua News Agency, Taipei, May 2 (Reporter Jia Wei and Chen Keying) Taiwan’s “Academia Sinica†Institute of Biomedical Research released the latest research results on the 2nd, stating that the over-expression of the oncogene paraspeckle Component 1 (PSPC1) in cancer cells will promote cancer. Cell proliferation, invasion, and metastasis. If we can suppress the performance of this gene in the future, we can reduce the growth and spread of cancer cells and help develop new cancer drugs. It is reported that relevant research papers have been published in the journal Nature Cell Biology recently.
The reporter learned from the press conference held on the day of the "Academia Sinica" that one of the main causes of death from cancer patients is the invasion and metastasis of cancerous tumor cells. Previous studies have found that the transmission of transforming growth factor-β1 (TGF-β1) signals It plays an important role in the mechanism of cancer metastasis. However, because this factor can both inhibit normal cell proliferation and promote cancer cell proliferation, invasion and metastasis, the scientific community is not aware of its role in different stages of cancer.
To find out the key factors of cell canceration, the relevant research team of this institution used whole genomes to analyze malignant tumors such as lung cancer, breast cancer, liver cancer, and prostate cancer. The search for tumor gene mutations, abnormal performance, and patient survival rates were performed. The genes.
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