Preparation methods and related requirements for experimental animal drinking water

Experimental animal drinking water does not have very clear water quality requirements, and generally follows the requirements of the National Standards of the People's Republic of China, Laboratory Animal Environment and Facilities, GB14925-2001:

1. The drinking water quality of common experimental animals meets the requirements of GB5749;

2. The drinking water of laboratory animals kept in the shielded and isolated environment shall be sterilized.

The commonly used experimental animal drinking water is prepared in the following ways:

1. autoclaving

Advantages: reliable sterilization, no pollution, no residue.

Disadvantages: 1) complicated operation and high labor intensity;

2) Long sterilization time;

3) Limited water production;

4) consume a lot of energy and water, and the cost is high;

5) Long-term disinfection water will cause water to form in the bottle, which will easily block the bottle mouth after falling off;

6) Only kill microorganisms, and can not effectively remove other pollutants.

2. Membrane filtration

Advantages: 1) Excellent water quality, can remove color, odor, disinfection by-product precursors and other microorganisms, organic matter;

2) stable water quality;

3) No need to add medicine or very little dose, no chemical;

4) Small footprint and easy to automate;

5) The amount of water is large.

Disadvantages: 1) High initial capital investment and operating costs;

2) The filter membrane has a service life and needs to be replaced within a certain period of time;

3) The operating cycle of the membrane depends on the pretreatment and reasonable working conditions, and is greatly affected by the process variation;

4) The generated wastewater is relatively clean, and direct discharge wastes resources.

3. Drinking water plus acid and alkali method

Advantages: 1) Effectively control the growth of Pseudomonas aeruginosa and Staphylococcus aureus (common pollution of clean grade animals);

2) Prevent secondary pollution of drinking water in animal laboratories.

Disadvantages: long-term feeding with acid drinking water will lead to a decline in reproductive rate

Customers usually choose to use membrane filtration to prepare experimental animal drinking water. The pure water system of SPRING model single-stage reverse osmosis process produced by Ruisijie Purification Technology Co., Ltd. is equipped with a built-in UV sterilizing device, and a sterilizing filter is additionally installed. It can meet the drinking water needs of experimental animals, no matter from water quality, economy, stability, ease of use, far exceeds the other two preparation methods.