The chromatography cabinet is a special-purpose cryogenic cabinet specially developed for biochemical chromatography experiments. It can also be used in other experiments that require low temperature environment, or for refrigerating articles. After scientific design, the total height of the freezer is generally less than 2 meters, which is convenient for entering and leaving the room and the elevator.
Second, the use of chromatography cabinet
It is mainly used in university disciplines and research institutes for life science research. It is mainly used for biochemical chromatographic analysis of various enzymes, peptides, macromolecules, nucleic acids and other substances. It can also be used in other experiments that require a low temperature environment, or for refrigerating items. Designed for a wide range of temperature-critical applications, it can operate chromatography equipment and other easily installed instruments and equipment in the box.
Third, the hardware composition of the chromatography cabinet
1 , refrigeration system
The standard refrigeration system consists of a compressor, a condenser, an evaporator, an expansion valve, a solenoid valve, and the like.
These devices are connected in turn by pipes to form a closed system. When the system is working, the compressor draws the low-temperature and low-pressure refrigerant vapor generated by the evaporator into the cylinder, and after the compressor compresses, the pressure rises (the temperature also rises) to be slightly larger than the pressure in the condenser. The high-pressure refrigerant vapor in the cylinder is discharged into the condenser. (The compressor acts as a compression and transport refrigerant). The high temperature and high pressure refrigerant vapor in the condensation exchanges heat with the lower temperature air (or normal temperature water) to condense into a liquid refrigerant. At this time, the liquid refrigerant expands. After the valve is cooled (depressurized), it enters the evaporator and absorbs the heat of the cooled object in the evaporator and then vaporizes. Thus, the object to be cooled is cooled and the refrigerant vapor is sucked away by the compressor, so that one cycle is completed in the refrigeration system by compression, condensation, expansion, and evaporation.
The principle of the refrigeration system is shown below:
2 , temperature control system
The core component of the temperature control system is the temperature sensor. The temperature sensor automatically samples and monitors the ambient temperature. When the ambient temperature is higher than the control set value, the control circuit starts, and the control hysteresis can be set. If the temperature is still rising, when the temperature rises to the set over-limit alarm temperature point, the over-limit alarm function is activated. When the controlled temperature cannot be effectively controlled, in order to prevent the destruction of the device, the function of the trip can be used to stop the device from continuing to operate.
The temperature control system is an important hardware in the chromatography cabinet. It mainly depends on the sensitivity, quantity and distribution of the sensor. The temperature control performance should also be concerned. Generally speaking, the temperature control range, temperature control accuracy and other parameters are temperature controllers. Decided, and the relationship with the chromatography cabinet is not large, some temperature control systems can control a wide temperature range, but the actual temperature control needs to be determined according to the refrigeration system of the chromatography cabinet itself; temperature control uniformity also needs and chromatography The combination of the cabinets has a good effect.
3 , air duct design
The air duct design inside the chromatography cabinet is the most easily overlooked part of the manufacturer. Whether the air duct design is reasonable or not directly affects the temperature stability and uniformity of the chromatography cabinet, which directly affects the overall use effect. The design of the interior of the chromatography cabinet should take into account the difference in the specific gravity between the cold air and the hot air. The active air supply of the fan is used to form an active and uniform air flow in the entire cabinet. It is also necessary to consider whether a short-range air circulation or a door opening is required. The influence on the airflow of the cabinet should be minimized, the design of the air supply capacity of the fan, and the like.
Chromatography cabinet internal air flow diagram
4 , chromatography cabinet accessories
Multi-functional chromatography cabinets can generally meet the requirements of chemical storage in order to meet the requirements of chromatographic experiments, so as to improve the efficiency of the use of chromatography cabinets. Therefore, the columns and clamps of the fixed chromatography column should be configured first, and then the configuration should be placed. The shelf of the equipment (can have a certain load-bearing capacity), in addition to the internal power supply, generally should be waterproof and leak-proof socket; the drug storage function needs to be configured with a corresponding number of shelves, and requires energy and chromatography The shelves are replaced and the columns and clips used for chromatography should be removable or not affecting the placement of the drug storage rack.
Fourth, the main performance indicators of the chromatography cabinet
The chromatography cabinet is a low-temperature cabinet. The core function is to provide a low-temperature environment. Therefore, the temperature performance index is the most important indicator, such as temperature uniformity, temperature stability, temperature control accuracy, and of course, temperature performance. The aspect indicator is the final performance. Its quality is guaranteed by hardware performance and design, such as: compressor performance, fan performance, design of the entire refrigeration system, thickness of the cabinet, quality of foaming, interior of the cabinet. Design, duct design and more.
In general, several performance indicators of compressor performance, internal air duct design, and temperature uniformity should be strongly concerned. The quality of the compressor guarantees the performance and stability of the refrigeration system; the internal air duct design can ensure a reasonable cold air flow inside the cabinet, so that the temperature control system can achieve the best control effect; the temperature uniformity is the whole cabinet The concentrated performance of the overall performance.
Source: Xiamen Guoyi Scientific Instrument Co., Ltd.
Frozen Shelled shrimps,Frozen Bamboo shrimp,Frozen Red shrimp
Zhejiang ocean family co.,ltd , https://www.ocean-family.com