Japanese research found that herpes zoster virus infects nervous tissue

Release date: 2009-12-23


Japanese researchers reported on the 22nd online edition of the Proceedings of the National Academy of Sciences that they found that varicella-zoster virus infects nerve tissue by attaching to the protrusions on the surface of nerve cells.
Varicella-zoster virus can cause two different diseases, namely chickenpox and herpes zoster, in which chickenpox is more common in children, and herpes zoster is more common in adults.
Researchers from institutions such as Osaka University and Kobe University in Japan infected human cultured cells with varicella-zoster virus and herpes simplex virus, respectively. As a result, both viruses were attached to the neurites on the surface of the cultured cells called "MAG", and then the genes were introduced into the host cells to proliferate.
The researchers also confirmed through this experiment that if antibodies are used to block the binding of neurite outgrowth and neurites, the virus is difficult to infect nerve tissue. This research helps develop new ways to prevent the infection of varicella-zoster virus. Meditech Medical Network

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