Quick Details of Bivalirudin:
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Product Name | Bivalirudin |
Synonyms | BIVALIRUDIN;BIVALIRUDIN TRIFLUOROACETATE;Bivalirudin, TFA;BITTERMELONP.E;Human Bivalirudin;Bivalirudin Acetate;Bivalirudin BG 8967, Hirulog, Hirulog I;BG 8967, Hirulog, Hirulog I |
CAS No. | 128270-60-0 |
Molecular Formula | C98H138N24O33 |
Molecular Weight | 2180.29 |
Density | 1.52 g/cm3 |
Refractive index | 1.675 |
Single Impurity (HPLC) | 1.0%max |
Amino Acid Composition | ±10% of theoretical |
Peptide Content (N%) | ≥80.0% |
Water Content (Karl Fischer) | ≤8.0% |
TrifluoroAcetate Content(HPIC) | ≤12.0% |
Storage Conditions | - 20°C |
MS (ESI) | Consistent |
Mass Balance | 95.0~105.0% |
Appearance | White freeze-dried powder |
Purity | 99% |
Quality Standard | Enterprise standard |
Packing | 12mg/vial |
Shipment | EMS;DHL;FedEx;TNT;UPS |
Delivery Time | 3-5 Working Days |
Payment terms | T/T;Western Union;Money Gram;Bitcoin |
Usage | For unstable angina and before and after ischemic complications. |
Bivalirudin  Descriptions:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Chemically, it is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech Hirudo medicinalis).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore, it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials. Patients receiving bivalirudin had fewer adverse events compared to patients that received heparin.
Bivalirudin  Applications:
Regardless of whether it is thrombin in the blood circulation or thrombin combined with thrombus, bivalirudin can specifically bind to its catalytic site and anion binding site, thereby directly inhibiting the activity of thrombin, and its characteristic is short-lived. ,reversible. Early clinical studies have shown that bivalirudin has a definite anticoagulant effect and has a lower incidence of bleeding events and is safer than traditional heparin anticoagulant therapy. It is mainly used to prevent angioplasty interventional treatment of ischemic complications of unstable angina.
In vitro, this product has both inhibitory effects on both soluble and thrombin-bound thrombin. This effect is not affected by the product of platelet release, and prolongs plasma activated partial thromboplastin time, coagulation in a dose-dependent manner. Enzyme time and prothrombin time. Suitable for percutaneous coronary intervention (PCI) for unstable angina.
Our order process:
Step 1 | Please tell me in what products you are interested including CAS number, quantities, and the destination country. |
Step 2 | You confirm all details and offer us purchase order. |
Step 3 | We offer the quotation of products and suitable shipping method for reference. |
Step 4 | You confirm the order and pay money 100% in advance and send us your contact information including contacting person,address,mobile number etc. |
Step 5 | We arrange the shipment according to your requirements and tracking number will be offered after confirming the payment within 24h |
Step 6 | We offer after-sales service after you receive products. |
Our competitive advantages:
Rich experience | Our company is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying. |
Wide range of export | Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month. |
High customs pass guaranteed. | Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand. |
Fast leading time | Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours. |
High quality, good price, fast and safety delivery. | Shipment by EMS ,FEDEX,DHL,TNT, UPS ,etc |
Quick Details of Bivalirudin:
Â
Product Name | Bivalirudin |
Synonyms | BIVALIRUDIN;BIVALIRUDIN TRIFLUOROACETATE;Bivalirudin, TFA;BITTERMELONP.E;Human Bivalirudin;Bivalirudin Acetate;Bivalirudin BG 8967, Hirulog, Hirulog I;BG 8967, Hirulog, Hirulog I |
CAS No. | 128270-60-0 |
Molecular Formula | C98H138N24O33 |
Molecular Weight | 2180.29 |
Density | 1.52 g/cm3 |
Refractive index | 1.675 |
Single Impurity (HPLC) | 1.0%max |
Amino Acid Composition | ±10% of theoretical |
Peptide Content (N%) | ≥80.0% |
Water Content (Karl Fischer) | ≤8.0% |
TrifluoroAcetate Content(HPIC) | ≤12.0% |
Storage Conditions | - 20°C |
MS (ESI) | Consistent |
Mass Balance | 95.0~105.0% |
Appearance | White freeze-dried powder |
Purity | 99% |
Quality Standard | Enterprise standard |
Packing | 12mg/vial |
Shipment | EMS;DHL;FedEx;TNT;UPS |
Delivery Time | 3-5 Working Days |
Payment terms | T/T;Western Union;Money Gram;Bitcoin |
Usage | For unstable angina and before and after ischemic complications. |
Bivalirudin  Descriptions:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Chemically, it is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech Hirudo medicinalis).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore, it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials. Patients receiving bivalirudin had fewer adverse events compared to patients that received heparin.
Bivalirudin  Applications:
Regardless of whether it is thrombin in the blood circulation or thrombin combined with thrombus, bivalirudin can specifically bind to its catalytic site and anion binding site, thereby directly inhibiting the activity of thrombin, and its characteristic is short-lived. ,reversible. Early clinical studies have shown that bivalirudin has a definite anticoagulant effect and has a lower incidence of bleeding events and is safer than traditional heparin anticoagulant therapy. It is mainly used to prevent angioplasty interventional treatment of ischemic complications of unstable angina.
In vitro, this product has both inhibitory effects on both soluble and thrombin-bound thrombin. This effect is not affected by the product of platelet release, and prolongs plasma activated partial thromboplastin time, coagulation in a dose-dependent manner. Enzyme time and prothrombin time. Suitable for percutaneous coronary intervention (PCI) for unstable angina.
Our order process:
Step 1 | Please tell me in what products you are interested including CAS number, quantities, and the destination country. |
Step 2 | You confirm all details and offer us purchase order. |
Step 3 | We offer the quotation of products and suitable shipping method for reference. |
Step 4 | You confirm the order and pay money 100% in advance and send us your contact information including contacting person,address,mobile number etc. |
Step 5 | We arrange the shipment according to your requirements and tracking number will be offered after confirming the payment within 24h |
Step 6 | We offer after-sales service after you receive products. |
Our competitive advantages:
Rich experience | Our company is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying. |
Wide range of export | Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month. |
High customs pass guaranteed. | Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand. |
Fast leading time | Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours. |
High quality, good price, fast and safety delivery. | Shipment by EMS ,FEDEX,DHL,TNT, UPS ,etc |
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