Ultrapure water equipment can remove impurities in water during the process of water production. The purity of water is relatively high. At this time, ultrapure water is easily contaminated. So how do we guarantee water quality in the process of using ultrapure water equipment? Today we will To analyze it?
The water prepared by ultrapure water equipment has high storage requirements and cannot be in contact with air, otherwise it will react with air and cause pollution. Because the ultrapure water extracted from the system is of high purity, our water quality cannot be guaranteed as long as it is in contact with air. Specifically, we need to pay attention to the following two major points:
First, take water
1. When taking ultra-pure water, the initial effluent must be drained to obtain stable water quality.
2. When the water is taken, let the ultrapure water flow along the side wall of the container. Try not to let the bubbles generate, which can reduce the air pollution.
3. Do not place the water storage tank in direct sunlight. The water temperature rises and it is easy to cause microbial growth. In particular, translucent water storage buckets can also cause algae to multiply due to daylight penetration.
4. When taking ultra-pure water, the initial effluent must be drained to obtain stable water quality.
Second, long time no equipment precautions
1. The types of impurities filtered by ultrapure water equipment can be distributed to each small step. For example, if the primary filtration in the pretreatment is not used for a long time, the bacteria and microorganisms on the surface of the filter element will grow, so that once the instrument is running, These contaminants must be brought into other filters entering the instrument. Although the reverse osmosis membrane can remove more than 90% of the impurities, a small amount of impurities will enter the next stage.
2 , ion exchange resin will not be contaminated by microorganisms for a long time, because the instrument will be a microbial culture medium if the resin is not used for a long time, so once the ultrapure water is taken, the contaminated impurities will definitely flow out, so the ultrapure water will definitely not reach The requirements of the analytical test will interfere with the experimental data and will bring unnecessary trouble to the customer.
The introduction on how to ensure the water quality of ultrapure water equipment is here. In the process of using ultrapure water equipment, how to ensure the quality of ultrapure water is very important. Ultra-pure water equipment has been widely used in the water treatment industry in recent years and has been well received by various industries.
API Powder is fully defined in ICH Q7A as any substance or mixture of substances intended for use in the manufacture of pharmaceutical products and, when used in pharmaceutical products, as an active ingredient of pharmaceutical products. Such substances have pharmacological activities or other direct effects in the diagnosis, treatment, symptom relief, management or prevention of disease, or can affect the function or structure of the body. The active ingredient of a medicine. Only when an API is processed into a pharmaceutical preparation can it become a medicine for clinical application.
According to its source, apis are divided into chemical synthetic drugs and natural chemical drugs.
Chemical synthetic drugs can be divided into inorganic synthetic drugs and organic synthetic drugs. Inorganic synthetic drugs are inorganic compounds (very few are elements), such as aluminum hydroxide and magnesium trisilicate for the treatment of gastric and duodenal ulcer, etc. Organic synthetic drugs are mainly made of basic organic chemical raw materials, through a series of organic chemical reactions and drugs (such as aspirin, chloramphenicol, caffeine, etc.).
Natural chemical drugs can also be divided into biochemical drugs and phytochemical drugs according to their sources. Antibiotics are generally produced by microbial fermentation and belong to the category of biochemistry. In recent years, a variety of semi-synthetic antibiotics are the combination of biosynthesis and chemical synthesis products. Among apis, organic synthetic drugs account for the largest proportion of variety, yield and output value, which is the main pillar of chemical pharmaceutical industry. The quality of the API determines the quality of the preparation, so its quality standards are very strict. All countries in the world have formulated strict national pharmacopoeia standards and quality control methods for the widely used APIS.
Specific API after processing -- pharmaceutical preparations
The term API is used mainly in relation to the finished product. Mainly raw materials obtained by chemical processing means, supply raw materials for the production of finished drugs. For example, cefpirome sulfate for injection is a drug, then cefpirome sulfate is an API
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