Release date: 2016-04-21
Recently, researchers from Nanchang University have developed a capsule that can be used in a bandage, which contains antibacterial drugs. The capsule can be controlled by the user to help it fight against resistant bacteria.
The smart bandage contains silver nanoparticles (AgNPs) that are wrapped in a layer of carbon beneath a layer of phosphate buffered saline (PBS). The user only needs to press the bandage, which will lead to layer interaction and release antibacterial silver particles.
Bacterial strains that are resistant to many drugs are an increasingly common and increasingly dangerous threat to humans in the 21st century. To this end, doctors need an innovative device that provides accurate, immediate delivery of antimicrobial agents that make the bacteria uncomfortable.
Recently, Wang Xiaolei, a professor at the School of Chemistry at Nanchang University, and his colleagues developed a special antibacterial material, which is mainly a silver nanoparticle enclosed in a carbon film, which can be used as a switchable capsule. According to Tiangong, this supramolecular capsule can regulate the activity of antibacterial silver particles, so it has three different switchable modes - packaging, opening and closing. In addition, it is worth mentioning that this material can also be 3D printed into various shapes for a wide range of applications, such as smart caps in culture bottles.
3D printed culture bottle intelligent antibacterial cap using this material
Professor Wang Xiaolei said that they had achieved an unexpected phenomenon in the transmission electron microscope image and obtained this result. In microscopic images, these capsules appear to be like plastic wrap for everyday packaging of fruit.
In order to verify the characteristics of these capsules, Professor Wang Xiaolei's research team combined them with plaster. The resulting smart bandage consists of two layers: the top layer contains sterilized phosphate buffered saline and the bottom layer contains the antimicrobial capsule. The user simply presses to cause interaction between the layers, releasing the active silver particles, and the color of the bandage changes from white to orange, indicating that the bandage is open. And if these silver particles are brought together, their antibacterial action is turned off.
David Mills, a bioactive therapist from Louisiana Polytechnic University, said he was impressed with the research, saying that the switchable antibacterial device is an excellent example of a fusion of nanotechnology, chemistry and materials science, as well as 3D printing versus biology. The impact of the medical field. “Wang’s team is helping to achieve a future where medical care is based on an on-demand, highly personalized approach that can be tailored to the patient’s individual specificity.â€
Source: China Science and Technology Network - Technology Daily
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