In piglet culture, some farmers use zinc oxide and antibiotics to prevent diarrhea in weaned piglets. After large doses of zinc oxide and antibiotics are added, although the phenomenon of diarrhea in piglets is reduced, other adverse effects are often caused.
First, heavy metal pollution
When the amount of zinc is not strictly controlled, the heavy metal content of the pork after slaughter may be exceeded. In addition, the zinc excreted in pig manure can also cause environmental problems.
Second, the nutritional interaction
High concentrations of zinc can lead to the production of excess metallothionein. Metallothioneins are metal-binding proteins produced by microorganisms and plants, short peptides rich in cysteine, and high affinity for various heavy metals. The metals that bind to them are mainly cadmium, copper and zinc. The preferential binding of this metallothionein to copper may lead to insufficient body trace elements.
Studies of interactions between zinc and enzymes have shown that pharmacological doses of zinc can affect phytase activity and have a negative impact on phytic acid release. This means that the decreased activity of phytase can affect the animal's possible lack of phosphorus.
Zinc oxide and acid have strong binding ability. High doses of zinc oxide can antagonize organic acids in feed.
Third, zinc poisoning
Long-term use of zinc oxide can cause piglet poisoning and even organ failure.
Fourth, cause drug resistance
Excessive addition of zinc to animal feeds increases the synthesis of bacteria and reduces the susceptibility of bacteria to antibiotics.
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