During the test and commissioning of the forced feeding device, some problems were found and further analysis is now carried out.
1 The problem of powder leakage and powdering in the forced feeding device contains fine powder components in the intermediates of pharmaceutical production. During the pressing process, the powder leakage phenomenon of the forced feeding device often occurs, mostly due to the hopper and forced feeding. The connection parts of the device are not tightly matched. For tantalum powder, it is mainly because the matching of the forced feeding device and the plane of the turntable is not precise, which can be carefully observed and analyzed. Solving these problems depends on the manufacturing process of the manufacturer and the manufacturing precision of the processing equipment. Therefore, when processing these key components, special equipment, tooling, CNC machine tools and scientific processes must be guaranteed to ensure the processing. Precision.
2 The weight difference analysis of tablets affects the difference in tablet weight. There are many requirements for the forced feeding device. 2: (1) does not change the original state of the material; (2) has good fluidity, To meet the filling requirements.
3 factors affecting the disintegration of tablets factors affecting the disintegration of tablets are 3: the composition of the material; the state of the material, mainly refers to the density, particle size; pressure of pressing.
During the course of our experiment, we found that the problem of disintegration of the tablets filled out by the natural feeding system and the forced feeding device is different under the same three factors, and the filling pressure is filled by the natural feeding system. The degree of disintegration of the tablets obtained meets the requirements, and the degree of disintegration of the tablets filled by the forced feeding system is not satisfactory.
In addition, the same is the forced feeding device, the disintegration degree of the tablets extruded by different models is also different. The reason for the analysis is mainly because the material changes the original state of the material during the filling process of the forced feeding device, and the fine powder in the material increases, and the disintegration degree is different. The more fine powder, the longer the disintegration time, the less the fine powder, and the shorter the disintegration time.
Therefore, it is necessary to remind the relevant designers to design the part, not only to meet the requirements of ordinary materials, but also to design different materials for customers.
1 The problem of powder leakage and powdering in the forced feeding device contains fine powder components in the intermediates of pharmaceutical production. During the pressing process, the powder leakage phenomenon of the forced feeding device often occurs, mostly due to the hopper and forced feeding. The connection parts of the device are not tightly matched. For tantalum powder, it is mainly because the matching of the forced feeding device and the plane of the turntable is not precise, which can be carefully observed and analyzed. Solving these problems depends on the manufacturing process of the manufacturer and the manufacturing precision of the processing equipment. Therefore, when processing these key components, special equipment, tooling, CNC machine tools and scientific processes must be guaranteed to ensure the processing. Precision.
2 The weight difference analysis of tablets affects the difference in tablet weight. There are many requirements for the forced feeding device. 2: (1) does not change the original state of the material; (2) has good fluidity, To meet the filling requirements.
3 factors affecting the disintegration of tablets factors affecting the disintegration of tablets are 3: the composition of the material; the state of the material, mainly refers to the density, particle size; pressure of pressing.
During the course of our experiment, we found that the problem of disintegration of the tablets filled out by the natural feeding system and the forced feeding device is different under the same three factors, and the filling pressure is filled by the natural feeding system. The degree of disintegration of the tablets obtained meets the requirements, and the degree of disintegration of the tablets filled by the forced feeding system is not satisfactory.
In addition, the same is the forced feeding device, the disintegration degree of the tablets extruded by different models is also different. The reason for the analysis is mainly because the material changes the original state of the material during the filling process of the forced feeding device, and the fine powder in the material increases, and the disintegration degree is different. The more fine powder, the longer the disintegration time, the less the fine powder, and the shorter the disintegration time.
Therefore, it is necessary to remind the relevant designers to design the part, not only to meet the requirements of ordinary materials, but also to design different materials for customers.
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