New progress in curbing super-resistant bacteria for doctors

New progress in curbing super-resistant bacteria for doctors

May 17, 2018 Source: Science and Technology Daily

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The issue of antibiotic resistance has always been the focus of the medical community. In particular, the emergence of carbapenem-resistant strains poses enormous challenges to global public health. The World Health Organization released the first list of antibiotic resistance "key pathogens", a total of 12 categories of 12, of which carbapenem resistance ranked first.

Recently, Peking Union Medical College Hospital reported that the isolation rate of carbapenem-resistant Enterobacteriaceae has decreased from 22% in 2015 to 8% in 2017 at the 2017 Medical Achievement Awards Review Meeting; Data analysis of drug changes for 10 years showed that the detection rate of methicillin-resistant Staphylococcus aureus in the hospital decreased from 56.5% in 2007 to 27.0% in 2016, which was significantly lower than the national average of 38.4% announced in 2016; The detection rate of vancomycin-resistant enterococci remained at around 3% in the past 10 years, and it was in the middle and lower levels in the country.

According to reports, Peking Union Medical College Hospital has continued to exert its strength in the sensory management system, technical system and informatization construction for many years. The role of the multidisciplinary expert team and the effective implementation of the sensory measures are the important reasons for handing over this answer sheet. . In view of the need to “downgrade” the use of preventive antibiotics, the Institute took the lead in launching the Antibacterial Drug Management Project (ASP) in China in December 2015, drawing on the advanced experience of the United States and Singapore. The medical department led the establishment of a multi-disciplinary team of more than a dozen experts from the Department of Institutions of Infection, Internal Medicine, Pharmacy, Laboratory, Information Management, etc. The first batch of selected cases was relatively clear and the amount of antibacterial drugs was used. The large surgical department, as the object of “housekeeping supervision”, conducts dynamic interventions such as real-time monitoring, evaluation, feedback and adjustment on the use of carbapenems and fluoroquinolones in hospitalized patients. The ASP project has been implemented for more than two years, which has greatly promoted the optimization of the use of carbapenems and fluoroquinolone antibiotics: the total amount of preventive antibacterial drugs in hospitals has decreased, the level of drugs has been reduced, and the use of indicators has been more precise. The overall level has improved. (Correspondent Duan Wenli Liu Xiaokun Fu Tanzhen)

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