The Freeze Dryer consists of a refrigeration system, a vacuum system, a heating system, and an electrical instrument control system. The main components are drying ovens, condensers, refrigeration units, vacuum pumps, heating/cooling devices, etc. It works by freezing the dried item below the triple point temperature and then sublimating the solid water (ice) in the item to water vapor under vacuum conditions, removing it from the item and drying the item.
The lyophilization process consists of three stages of pre-freezing, sublimation and re-freezing. The basic principle of freeze-drying is the mechanism of heat and mass transfer under low temperature and low pressure. In the process of freeze-drying, it is necessary to monitor the temperature of the product and the temperature of the shelf and the temperature inside the box to ensure the quality of the drug and achieve energy saving and consumption reduction. Reduce production costs and bake.
Technical requirements for lyophilizer temperature sensor:
1. Measurement range: freeze-drying temperature: -80 °C, freeze-drying machine sterilization temperature <130 °C, temperature sensor temperature measurement range -80-150 °C;
2. Outline structure: The size of the thermal resistance probe is required to be as small as possible, so as to insert the medicines of different sizes to measure the temperature of the medicine;
3. Measurement accuracy: The measurement accuracy conforms to the PT100 Class A standard, and the accuracy is required to reach the Class A standard when measuring at low temperature;
4, stability, repeatability requirements: the same product repeatability measurement error < 1 ° C;
5. Consistency: < 1 ° C between different cores or different products of the same product;
6, product insulation: thermal resistance internal resistance is strictly prohibited to shell, and must withstand voltage AC500V;
7. Product tightness and sealing requirements: The probe protection tube and the wire must be tightly sealed, the tensile force is not less than 50N, and the sealing performance is not less than IP67 protection level;
8. Material requirements: The probe, wire and sealant of the temperature sensor meet the requirements of GMP, FDA, 3A and other standards.
For the measurement of the temperature of the freeze dryer, the company introduced a small probe and a stable and reliable PL7104 wire type thermal resistance:
Freeze dryer small probe thermal resistance - PL7104 wire type thermal resistance features:
1. The thermal resistance adopts imported PT100 thermal resistance, and the aging screening process ensures that all assembled components are stable and reliable;
2, Φ2 * 7.5mm tiny probe, small size and fast thermal response, can be placed in most of the bottles to measure;
3, temperature range: -100-200 ° C, suitable for freeze drying and equipment sterilization process;
4. Measurement accuracy is above grade A, measurement error <0.5 °C, repeatability measurement error <0.75 °C, measurement error between different cores or different products < 0.75 °C;
5. The product adopts imported sealant and adopts mechanical belt pressure automatic filling rubber sealing process, the tensile strength reaches 55N, and the sealing performance reaches IP68 protection grade;
6, the product uses advanced insulation technology, PT100 core and shell insulation, withstand voltage > AC1000V;
7, all stainless steel protection tube, all PTFE cable, food grade sealant, in line with GMP, FDA, 3A and other standards.
Freeze dryer small probe thermal resistance—PL7104 wire type thermal resistance application field:
Freeze-drying, cooking and drying processes in the pharmaceutical and food industries, sterilization equipment, heating equipment, and electric, metallurgical, glass, chemical, rubber and textile industries.
Cold Chain Products,Medical Refrigerator,Platelet Incubator,Car Refrigerator
Guangdong Widinlsa International Co.Ltd , https://www.gdwidinlsa.com