At 4 o'clock on the afternoon of September 7, 2016, actress Xu Ting died of acute lymphoma and lung infection in Beijing 304 Hospital, only 26 years old. Although not a big star, the girl’s life and condition have become the focus of today.
Cancer is the center of fear for people
"Humans use genes to describe the journey of cancer, and there is still a long way to go." -- Jessica Wapner, book "Philadelphia chromosome: genetic mutations and the exploration of cancer at the genetic level."
On July 16, 2016, Zhang Hua (pseudonym)'s father died of lung cancer. From the examination of lung cancer to the death, the whole process only took 9 weeks. This is a huge psychological blow to Zhang Hua. After the death of his father, in addition to grief, Zhang Hua’s reaction was: to do a whole body cancer genetic test for himself. She heard people say that family members of the family have cancer, and there is a high probability that they will "geneticize" to cancer.
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"Send some money and rest assured." Zhang Hua said, "In addition to my father, my immediate family members also have grandfather and aunt who have cancer. Now I am married and will be born. I don't want my child to face premature death. mother."
Due to the cost difference between agencies and the impact of intermediary profits, the price difference of genetic testing for cancer is very large. In China, the whole genetic testing can be priced up to 60,000 to 70,000, and sometimes low can be done in 15,000.
"I was inquiring about a testing agency in Wuhan. I recommended it to my friends. I told me that it is the largest genetic laboratory in Asia. It can do a whole group of genetic sequencing for healthy people, about fifty or sixty thousand." Zhang Hua said, "There are also suggestions. I went to the United States to do the whole group of genes for healthy people, charging between tens of thousands and hundreds of thousands."
In February 2013, Angelina Jolie decided to remove the double breast. Julie's mother suffered from ovarian cancer for nearly 10 years. At the age of 56, she eventually died after her first grandson was born. As a mother of six children, Julie went to test her genes. The test report showed that she carried the cancer susceptibility gene BRCA1 (Breast Cancer Susceptibility Gene 1), a gene closely related to breast cancer. The doctor told her that her chance of developing breast cancer is about 87% and the chance of ovarian cancer is 50%.
“After surgery, my chances of developing breast cancer have dropped from 87% to 5%,†Julie said in a letter to the New York Times. “Now, I can tell the children that mothers will not suffer from breast cancer. And died." Just two years later, in March 2015, Julie removed her ovaries.
Because of Angelina Jolie, cancer genetic testing is coming to the public eye. Nowadays, more and more women choose to remove the breast and ovaries before they get the tumor.
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Angelina Zhu Lizhuan wrote in an open letter to "My medical choice (My Medical Choice)" chose to do BRCA detected after women increased by 40%.
In January 2016, President Obama announced in the State of the Union address a “National Cancer Lunar Plan†directly led by Vice President Biden, which funded a total of one billion US dollars for related cancer research, meaning the moon landing plan of the 1960s. Humans will eventually overcome cancer." The program will coordinate more than a dozen agencies, including the US Department of Defense, the US Food and Drug Administration, the National Institutes of Health, and the National Science Foundation, to double the pace of cancer surveillance within five years.
However, “this task is arduous and complex. At present, human understanding of genes is not enough to bring real benefits to cancer patients.†Jessica Wapner in Science American 2016 Written in the monthly magazine. Previously she was the author of "Philadelphia chromosome: genetic mutations and the exploration of cancer from the gene level."
“We are still in a transitional phase,†said Stephen Chanok, director of cancer epidemiology and genetics research at the American Cancer Research Center.
Cancer genetic testing has been in clinical practice since 1995, and scientists have established a number of genes related to cancer. But the problem is far from simple. How useful is cancer gene sequencing?
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